| Cat. No. |
Product Name |
Information |
| PC-42038 |
PQR-620
mTOR inhibitor
|
PQR-620 (PQR620) is a potent and selective, brain penetrant inhibitor of mTORC1/2, displays >1000-fold selectivity towards mTOR over PI3Kα in enzymatic binding assays. |
| PC-45102 |
CC-115 hydrochloride
DNA-PK/mTOR inhibitor
|
CC-115 hydrochloride is a potent, dual inhibitor of mTOR and DNA-PK with IC50 of 21 nM and 13 nM, respectively. |
| PC-42464 |
Rapamycin
mTOR inhibitor
|
Rapamycin (Sirolimus) is a macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM), induces autophagy. |
| PC-26526 |
eALM1137
mTOR inhibitor
|
eALM1137 is a highly potent, selective mTOR inhibitor with IC50 of 4.8 nM, weakly inhibits DNA-PK with IC50 of 77 nM (17-fold selectivity). |
| PC-24226 |
TMBIM6 inhibitor BIA
TMBIM6 inhibitor
|
TMBIM6 inhibitor BIA is a specific inhibitor of TMBIM6 (BAX inhibitor-1, BI-1), prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, also suppresses ER release of Ca2+ from TMBIM6, has broad anticancer activities. |
| PC-62011 |
CIDD 0067106
|
CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM). |