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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-mTOR

Request The Product List ofmTOR mTOR

Cat. No. Product Name Information
PC-42038

PQR-620

mTOR inhibitor

PQR-620 (PQR620) is a potent and selective, brain penetrant inhibitor of mTORC1/2, displays >1000-fold selectivity towards mTOR over PI3Kα in enzymatic binding assays.
PC-45102

CC-115 hydrochloride

DNA-PK/mTOR inhibitor

CC-115 hydrochloride is a potent, dual inhibitor of mTOR and DNA-PK with IC50 of 21 nM and 13 nM, respectively.
PC-42464

Rapamycin

mTOR inhibitor

Rapamycin (Sirolimus) is a macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM), induces autophagy.
PC-26526

eALM1137

mTOR inhibitor

eALM1137 is a highly potent, selective mTOR inhibitor with IC50 of 4.8 nM, weakly inhibits DNA-PK with IC50 of 77 nM (17-fold selectivity).
PC-24226

TMBIM6 inhibitor BIA

TMBIM6 inhibitor

TMBIM6 inhibitor BIA is a specific inhibitor of TMBIM6 (BAX inhibitor-1, BI-1), prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, also suppresses ER release of Ca2+ from TMBIM6, has broad anticancer activities.
PC-62011

CIDD 0067106

CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM).

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