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Aloe-emodin

Chemical Structure : Aloe-emodin

CAS No.: 481-72-1

Aloe-emodin (Aloe emodin, Rhabarberone)

货号: PC-27954Not For Human Use, Lab Use Only.

Aloe-emodin (Aloe emodin, Rhabarberone) is a natural hydroxyanthraquinone with antitumor activities, binds and inhibits mTORC2, inhibits both proliferation and anchorage-independent growth of PC3 cells, also inhibits HER-2 expression through the downregulation of Y-box binding protein-1 (YB-1), inhibits cancer metastasis and cancer stem cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Aloe-emodin (Aloe emodin, Rhabarberone) is a natural hydroxyanthraquinone with antitumor activities, binds and inhibits mTORC2, inhibits both proliferation and anchorage-independent growth of PC3 cells, also inhibits HER-2 expression through the downregulation of Y-box binding protein-1 (YB-1), inhibits cancer metastasis and cancer stem cells.

物理化学性质&存储条件

分子量 270.24
分子式 C15H10O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,8-Dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione

参考文献

1. Liu K, et al. Carcinogenesis. 2012 Jul;33(7):1406-11.

2. Shen F, et al. Eur J Pharmacol. 2020 Nov 5;886:173550.

3. Ma JW, et al. Oncotarget. 2016 Sep 13;7(37):58915-58930.

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