| Cat. No. |
Product Name |
Information |
| PC-38809 |
GNE551
TRPA1 agonist
|
GNE551 is a potent, selective, non-covalent agonist of TRPA1 ion channel with EC50 of 254 nM in Ca2+ influx assays. |
| PC-38676 |
Libvatrep
TRPV1 antagonist
|
Libvatrep (SAF312) is a potent, selective non-competitive inhibitor/antagonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1), shows potential for treatment of ocular surface pain. |
| PC-38603 |
Mesendogen
TRPM6 inhibitor
|
Mesendogen (Compound 6528694, MEG) is a small molecule inhibitor of TRPM6 channel, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells (hESCs) through alteration of magnesium homeostasis. |
| PC-38390 |
Evifacotrep
TRPC5 inhibitor
|
Evifacotrep is a potent selective transient receptor potential channel 5 (TRPC5) antagonist. |
| PC-38378 |
CA-008
TRPV1 agonist
|
CA-008 (Vocacapsaicin) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-73430 |
Motugivatrep
TRPV1 antagonist
|
Motugivatrep is a potent, selective transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-73351 |
ZINC17988990
TRPV5 inhibitor
|
ZINC 17988990 is a potent, selective inhibitor of TRPV5 mediated currents, inhibits rbTRPV5/hTRPV5 with IC50 of 106/177 nM, showing marked selectivity for TRPV5 over TRPV6. |
| PC-73245 |
GFB-8438
TRPC5 inhibitor
|
GFB-8438 is a potent, selective TRPC5 inhibitor with IC50 of 0.18 uM (hTRPC5, Qpatch assay). |
| PC-73173 |
ML-SI3
TRPML inhibitor
|
ML-SI3 is a synthetic inhibitor of TRPML calcium channel blocker with IC50 of 4.7 μM and 1.7 μM for TRPML1/2 channel respectively. |
| PC-73096 |
GSK3527497
TRPV4 inhibitor
|
GSK3527497 (GSK-3527497) is a potent, selective TRPV4 inhibitor with IC50 of 12 nM (hTRPV4). |
| PC-73026 |
(rel)-ML-SI
TRPML1 antagonist
|
ML-SI3 (Mucolipin-specific synthetic inhibitor 3) is a synthetic antagonist of transient receptor potential mucolipin 1 (TRPML1), prevents lysosomal calcium efflux and blocks downstream TRPML1-mediated induction of autophagy. |
| PC-73025 |
ML-SA1
TRPML1 agonist
|
ML-SA1 (Mucolipin-specific synthetic agonist 1) is a potent synthetic agonist for TRPML1. |
