| Cat. No. |
Product Name |
Information |
| PC-45355 |
Nonivamide
TRPV1 agonist
|
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel. |
| PC-26530 |
CMP233
TRPM4 antagonist
|
CMP233 is a potent, selective TRPM4 channel antagonist with IC50 of 0.15 uM. |
| PC-26527 |
TRPM4 inhibitor PBA
TRPM4 inhibitor
|
TRPM4 inhibitor PBA is a specific small molecule inhibitor of Ca2+-activated monovalent cation channel TRPM4 with IC50 of 339 nM using the fluorescence-based Na+-influx assay on HEK293 cells stably overexpressing hTRPM4. |
| PC-26459 |
IMTU
TRPV1 antagonist
|
IMTU is a potent and selective TRPV1 antagonist with IC50 of 128.34 nM, significantly inhibits the capsaicin-induced calcium influx. |
| PC-26458 |
HKC54
TRPV2 antagonist
|
HKC54 is a potent, selective TRPV2 antagonist with IC50 of 0.4 uM, 50-fold selectivity over TRPV1 and ∼70-fold selectivity over TRPA1. |
| PC-26401 |
RN-1665
TRPV4 antagonist
|
RN-1665 is a potent, selective and orally active TRPV4 antagonist with IC50 of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4, exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. |
| PC-26099 |
DWP05195
TRPV1 antagonist
|
DWP05195 (DWP-05195) is a transient receptor potential vanilloid 1 (TRPV1) antagonist. |
| PC-26098 |
Vocacapsaicin hydrochloride
TRPV1 agonist
|
Vocacapsaicin hydrochloride (CA-008) is a non-opioid, water-soluble and injectable prodrug of capsaicin, a potent agonist of TRPV1 channel. |
| PC-25977 |
TRPM8 inhibitor PBMC
TRPM8 antagonist
|
PBMC is a highly specific and potent TRPM8 antagonist with IC50 of 0.4-0.6 nM in whole-cell voltage clamp assays. |
| PC-25933 |
AV3-1
TRPV3 activator
|
AV3-1 (TRPV3 activator 1) is a specific small molecule TRPV3 activator with EC50 of 2.0 μM for mouse TRPV3 and 7.2 μM for human TRPV3. |
| PC-25855 |
Olvanil
TRPV1 agonist
|
Olvanil (NE-19550, N-Vanillyloleamide) is a potent, selective agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with EC50 of 0.7 nM. |
| PC-25854 |
Capsiate
TRPV1 agonist
|
Capsiate is a non-pungent capsaicin analog and potent, selective TRPA1 agonist, evokes inward currents at -60 mV in the HEK293 cells expressing TRPV1with EC50 of 290 nM. |
