| Cat. No. |
Product Name |
Information |
| PC-25342 |
Cathepsin D inhibitor N-8
Cathepsin D inhibitor
|
Cathepsin D inhibitor N-8 is a potent, specific inhibitor of Cathepsin D (CTSD) with SPR KD of 0.58 uM, effectively inhibits proliferation and induces apoptosis in leukemia cells with high CTSD expression. |
| PC-24193 |
Verducatib
Cathepsin C inhibitor
|
Verducatib (BI 1291583) is a potent, selective, reversible inhibitor of cathepsin C (CatC, DPP-1) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II). |
| PC-24134 |
Florensocatib
DPP-1 inhibitor
|
Florensocatib (HSK31858, CHF10196) is a highly potent, reversible, and selective DPP1 (Cathepsin C, CatC) inhibitor, reversibly inhibitsrecombinant DPP-1 activity with an IC 50 of 3.7 nM. |
| PC-22165 |
ASP1617
Cathepsin S inhibitor
|
ASP1617 (ASP-1617) is a potent, highly specific and orally active cathepsin S (CatS) inhibitor with IC50 of 4.6 nM and 0.39 nM for human and mouse CatS, respectively. |
| PC-21937 |
Balicatib
Cathepsin K inhibitor
|
Balicatib (AAE581) is a potent, selective and orally active and selective cathepsin K inhibitor with IC50 of 22 nM. |
| PC-21936 |
CA-074
Cathepsin B inhibitor
|
CA-074 is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM. |
| PC-21763 |
VBY-825
Cathepsin S inhibitor
|
VBY-825 is an reversible cathepsin inhibitor of cathepsins B, L, S and V with Ki values of 130/250/250/330/2.3/4.7 nM (cathepsin S/L/ZV/Bhumanized-rabbit cathepsin K/cathepsin F). |
| PC-20410 |
Z-Tyr-Ala-CHN2
Cathepsin L inhibitor
|
Z-Tyr-Ala-CHN2 is a potent cathepsin L inhibitor with EC50 of <50 nM, has broad-spectrum coronavirus antiviral activity. |
| PC-20203 |
Dutacatib
Cathepsin K inhibitor
|
Dutacatib (AFG495) is potent, selective and non-covalent cathepsin K inhibitor with IC50 of 3-6 nM (human CatK), shows excellent selectivity profile versus human cathepsins L and S. |
| PC-49223 |
MK-1256
Cathepsin K inhibitor
|
MK-1256 (MK1256) is a potent, selective cathepsin K (Cat K) inhibitor with IC50 of 0.62 nM, >1100-fold selectivity over Cat B, L, S, C, H, Z, and V, 110-fold over Cat F. |
| PC-38582 |
SID 26681509
Cathepsin L inhibitor
|
SID 26681509 is a potent, selective inhibitor of lysosome hydrolase cathepsin L with IC50 of 56 nM, displays no inhibitory activity at cathepsin G. |
| PC-73381 |
Calpeptin
Calpain inhibitor
|
Calpeptin is a potent, cell penetrating calpain inhibitor with ID50 of 40 nM for Calpain I in human platelets, also inhibits cathepsin K and is a potent and specific inhibitor of SARS-CoV-2 entry and some variants. |
