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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cathepsin-Calpeptin
Calpeptin

Chemical Structure : Calpeptin

CAS No.: 117591-20-5

Calpeptin

货号: PC-73381Not For Human Use, Lab Use Only.

Calpeptin is a potent, cell penetrating calpain inhibitor with ID50 of 40 nM for Calpain I in human platelets, also inhibits cathepsin K and is a potent and specific inhibitor of SARS-CoV-2 entry and some variants.

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10 mg ¥580 In stock
25 mg ¥980 In stock
50 mg ¥1580 In stock
100 mg ¥2580 In stock
250 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Calpeptin is a potent, cell penetrating calpain inhibitor with ID50 of 40 nM for Calpain I in human platelets, also inhibits cathepsin K and is a potent and specific inhibitor of SARS-CoV-2 entry and some variants.

物理化学性质&存储条件

分子量 362.46
分子式 C20H30N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate

参考文献

1. Tsujinaka T, et al. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1201-8.

2. Catalano JG, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22.

3. Sonia Mediouni, et al. SLAS Discov. 2022 Jan;27(1):8-19.

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