| Cat. No. |
Product Name |
Information |
| PC-27706 |
MRS2339
P2X receptor agonist
|
MRS2339 is a nucleotide analog agonist of cardiac P2X receptor, improves systolic function in heart failure. |
| PC-27681 |
P2X2/3 antagonist 30
P2X2/3 antagonist
|
P2X2/3 antagonist 30 is a potent, selective and allosteric antagonist with pIC50 of 8.4 (hP2X2/3), shows efficacious taste-blocking effect. |
| PC-27427 |
Femopixant
P2X2/3 antagonist
|
Femopixant is a potent, selective P2X3 and P2X2/3 receptor antagonist. |
| PC-27056 |
BTFA
P2X1 receptor inhibitor
|
BTFA is a specific small molecule P2X1 receptor inhibitor, binds to the top of the central vestibule and inhibits cation flux in a dose-dependent manner, inhibits the mixed-cation current of the mP2X1 receptor with IC50 of 4.3 uM. |
| PC-26954 |
EVT‑401
P2X7R antagonist
|
EVT-401 is a potent, highly selective human P2X7 receptor (P2X7R) antagonist with Ki of 7.6 nM in competitive binding assays. |
| PC-26328 |
Funopixant
P2X3 antagonist
|
Funopixant is a potent, selective P2X3 receptor antagonist with IC50 of 32.45 nM for hP2X3. |
| PC-26169 |
PSB-OR-2020
P2X4 antagonist
|
PSB-OR-2020 is a potent, selective P2X4 receptor antagonist, inhibits ATP-induced Ca2+ influx by in 1321N1 astrocytoma cells stably transfected with the human P2X4 receptor with IC50 of 6.32 nM, >300-fold selective over P2X1, P2X2, P2X3, and P2X7. |
| PC-26168 |
A-317491
P2X3 antagonist
|
A-317491 is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. |
| PC-26167 |
PSB-1011
P2X2 antagonist
|
PSB-1011 is a potent, moderately selective rat P2X2 receptor antagonist with IC50 of 79 nM, weakly inhibits P2X1 and P2X3 receptors and shows no activity against P2X4 and P2X7 receptors. |
| PC-26166 |
PSB-2014
P2X1 antagonist
|
PSB-2014 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 23.1 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors. |
| PC-26165 |
PSB-2001
P2X1 antagonist
|
PSB-2001 is a potent, selective and competitive P2X1 receptor (P2X1R) with IC50 of 19.2 nM, weakly inhibits P2X4, P2X7 and shows no activity against P2X2, P2X3 receptors. |
| PC-26164 |
NF023
P2X1 antagonist
|
NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors. |
