| Cat. No. |
Product Name |
Information |
| PC-27193 |
B0AT1 inhibitor compound 3
B0AT1 inhibitor
|
B0AT1 inhibitor compound 3 is a potent, selective, allosteric inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 513 nM and 295 nM for human and mouse B0AT1 respectively. |
| PC-27192 |
JX225
B0AT1 inhibitor
|
JX225 is a potent, high-affinity inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 0.07 uM in FLIPR assays, and 0.44 uM in radioactive L-leucine uptake assays. |
| PC-27190 |
Cinromide
B0AT1 inhibitor
|
Cinromide is an anticonvulsant agent and potent, selective neutral amino acid transporter B0AT1 (SLC6A19) inhibitor with IC50 of 0.5 uM. |
| PC-26980 |
Fluvoxamine
Serotonin reuptake inhibitor
|
Fluvoxamine is a selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor and selective sigma-1 receptor agonist, shows ntidepressant activities. |
| PC-26734 |
Sulfasalazine
SLC7A11/xCT inhibitor
|
Sulfasalazine (NSC 667219) is a disease-modifying antirheumatic drug used to treat arthritis and ankylosing spondylitis, is a SLC7A11/xc(-) cystine/glutamate antiporter (xCT) inhibitor, has anti-leukemic activity against primary AML samples. |
| PC-26223 |
Duloxetine
SNRI
|
Duloxetine (LY248686) is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) with Ki of 4.6 nM, also inhibitsvoltage-dependent K+ channels (Kv channels) with IC50 of 4.95 uM for arterial Kv currents. |
| PC-25865 |
(S)-Fluoxetine hydrochloride
SSRI
|
(S)-Fluoxetine hydrochloride (LY-110140) is a selective serotonin reuptake inhibitor (SSRI) antidepressant, inhibits the uptake of serotonin by neurons. |
| PC-25864 |
Fluoxetine hydrochloride
SSRI
|
Fluoxetine hydrochloride (LY-110140) is a selective serotonin reuptake inhibitor (SSRI) antidepressant, inhibits the uptake of serotonin by neurons. |
| PC-25863 |
Fluoxetine
SSRI
|
Fluoxetine (LY-110140 free base) is a selective serotonin reuptake inhibitor (SSRI) antidepressant, inhibits the uptake of serotonin by neurons. |
| PC-25786 |
Sertraline hydrochloride
SSRI
|
Sertraline hydrochloride is a selective serotonin reuptake inhibitor (SSRI) with antidepressant activity. |
| PC-24696 |
RDS-04-010
DAT inhibitor
|
RDS-04-010 is a novel atypical dopamine transporter (DAT) inhibitor with Ki of 245 nM (rDAT), binds to an inward-facing conformation of DAT. |
| PC-24214 |
Tetrabenazine
VMAT2 inhibitor
|
Tetrabenazine (Ro 1-9569) is a potent, reversible inhibitor of the vesicular monoamine transporter VMAT2 with Kd of 1.34 nM, shows potential for diseases related to hyperactive movement disorders such as Huntington's disease. |
