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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Milnacipran hydrochloride
Milnacipran hydrochloride

Chemical Structure : Milnacipran hydrochloride

CAS No.: 101152-94-7

Milnacipran hydrochloride (F2207, Midalcipran)

货号: PC-28025Not For Human Use, Lab Use Only.

Milnacipran hydrochloride (F2207, Midalcipran) is is an antidepressant agent via selective inhibiting the uptake of monoamines, inhibits the uptake of radiolabelled serotonin and noradrenaline with IC50 of 203 and 100 nM, respectively, but not dopamine, shows no inhibition of the activity of monoamine oxidase in vitro or in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Milnacipran hydrochloride (F2207, Midalcipran) is is an antidepressant agent via selective inhibiting the uptake of monoamines, inhibits the uptake of radiolabelled serotonin and noradrenaline with IC50 of 203 and 100 nM, respectively, but not dopamine, shows no inhibition of the activity of monoamine oxidase in vitro or in vivo.

物理化学性质&存储条件

分子量 282.81
分子式 C15H23ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, (1R,2S)-rel- hydrochloride

参考文献

1. Assie MB, et al. Neuropharmacology. 1992 Feb;31(2):149-55.

2. Moret C, et al. Neuropharmacology. 1985 Dec;24(12):1211-9.

3. Ansseau M, et al. Eur Neuropsychopharmacol. 1991 May;1(2):113-21.

4. Shuto S, et al. J Med Chem. 1996 Nov 22;39(24):4844-52.

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