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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Monoamine Transporter-Bupropion hydrochloride
Bupropion hydrochloride

Chemical Structure : Bupropion hydrochloride

CAS No.: 31677-93-7

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Bupropion hydrochloride (Amfebutamone hydrochloride)

货号: PC-28177Not For Human Use, Lab Use Only.

Bupropion hydrochloride (Amfebutamone) is an orally active, norepinephrine-dopamine reuptake inhibitor (NDRI), blocks dopamine (DA) uptake and Methamphetamine-induced DA release with IC50s of 1.76 uM and 14.2 uM, respectively, shows antidepressant activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bupropion hydrochloride (Amfebutamone) is an orally active, norepinephrine-dopamine reuptake inhibitor (NDRI), blocks dopamine (DA) uptake and Methamphetamine-induced DA release with IC50s of 1.76 uM and 14.2 uM, respectively, shows antidepressant activity.

物理化学性质&存储条件

分子量 276.20
分子式 C13H19Cl2NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Propanone, 1-(3-chlorophenyl)-2-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1)

参考文献

1. Linda D Simmler, et al. BMC Res Notes. 2013 Jun 5;6:220.

2. Piotr Tutka, et al. Eur J Pharmacol. 2004 Sep 19;499(1-2):117-20.

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