| Cat. No. |
Product Name |
Information |
| PC-61998 |
Edivoxetine hydrochloride
Norepinephrine reuptake inhibitor
|
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD). |
| PC-61997 |
Edivoxetine
Norepinephrine reuptake inhibitor
|
Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD).. |
| PC-61884 |
PF-184298
Monoamine reuptake inhibitor
|
PF-184298 is a potent, selective dual serotonin and noradrenaline monoamine reuptake inhibitor (SNRI) with IC50 of 6 nM and 21 nM, respectively. |
| PC-70169 |
Amitifadine
Monoamine reuptake inhibitor
|
Amitifadine (DOV-21947, EB-1010) is a triple monoamine reuptake inhibitor, inhibits the reuptake of 5-HT, norepinephrine and dopamine in HEK 293 cells with IC50 of 12, 23 and 96 nM, respectively. |
| PC-60053 |
Solriamfetol hydrochloride
|
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
| PC-45481 |
Diclofensine
Monoamine reuptake inhibitor
|
Diclofensine (Ro 8-4650) is an antidepressant that acts as a triple monoamine reuptake inhibitor. |
| PC-45480 |
Diclofensine hydrochloride
Monoamine reuptake inhibitor
|
Diclofensine (Ro 8-4650) hydrochloride is an antidepressant that acts as a triple monoamine reuptake inhibitor. |
| PC-46649 |
Paroxetine hydrochloride
GRK2 inhibitor, SSRI
|
Paroxetine hydrochloride is an oral, selective serotonin reuptake inhibitor (SSRI), also is a direct, selective inhibitor of G protein-coupled receptor kinase 2 (GRK2) with pIC50 of 5.6. |
| PC-45454 |
Amitifadine hydrochloride
Monoamine reuptake inhibitor
|
Amitifadine hydrochloride (DOV-21947 hydrochloride) is a triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
| PC-45076 |
Valbenazine
VMAT2 inhibitor
|
Valbenazine (NBI-98854) is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor with Ki of 110-190 nM. |
| PC-27478 |
Moleroxetine
SNRI
|
Moleroxetine is a serotonin and norepinephrin reuptake inhibitor (SNRI), can potently inhibits the activity of TRPA1. |
| PC-27444 |
Dapoxetine hydrochloride
SSRI
|
Dapoxetine hydrochloride (LY-210448) is a short-acting, orally active selective serotonin reuptake inhibitor (SSRI) for the treatment of premature ejaculation. |