| Cat. No. |
Product Name |
Information |
| PC-44607 |
UNC1215
L3MBTL3 inhibitor
|
UNC1215 (UNC-1215) is a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3 with Kd of 120 nM. |
| PC-42037 |
HLCL-61 hydrochloride
PRMT5 inhibitor
|
HLCL-61 hydrochloride is a potent and selective protein arginine methyltransferase PRMT5 inhibitor. |
| PC-42741 |
UNC0321
G9a inhibitor
|
UNC0321 (UNC-0321) is a highly potent, selective histone methyltransferase G9a inhibitor with Ki of 63 pM. |
| PC-45092 |
MI-503
Menin-MLL inhibitor
|
MI-503 (MI 503) is a highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM. |
| PC-42907 |
3-Deazaneplanocin A hydrochloride
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) hydrochloride is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42587 |
3-Deazaneplanocin A
EZH2 inhibitor
|
3-Deazaneplanocin A (DZNep) is a highly potent and competitive S-adenosylhomocysteine hydrolase inhibitor with Ki of 0.05 nM, also inhibits histone methyltransferase EZH2. |
| PC-42923 |
MM-102 trifluoroacetate
MLL1/WDR5 inhibitor
|
MM-102 trifluoroacetate is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-42922 |
MM-102
MLL1/WDR5 inhibitor
|
MM-102 is a high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM. |
| PC-45489 |
PFI-2 hydrochloride
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) hydrochloride is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-45488 |
PFI-2
SETD7 inhibitor
|
PFI-2 ((R)-PFI-2) is a first-in-class, potent and selective inhibitor of SETD7 methyltransferase with Ki app/IC50 of 0.33/2 nM, respectively. |
| PC-27203 |
TCIP3
p300/CBP-BCL-6 KAT-TCIP
|
TCIP3 is a cell-permeable lysine acetyltransferase TCIP (KAT-TCIP) and bivalent molecular glue degrader that binds dually to p300/CBP and BCL6, redirects p300/CBP to BCL6, exhibits potent anti-proliferative effect in DLBCL cells. |
| PC-27108 |
EZH2 inhibitor C36
EZH2-PRC2 inhibitor
|
EZH2 inhibitor C36 is a potent, selective and allosteric EZH2-PRC2 inhibitor with IC50 of 2.27 nM in AlphaLisa assays, inhibits both the basal and activated forms of the PRC2 complex containing EZH2, but not EZH1, in a SAM-noncompetitive manner. |
