| Cat. No. |
Product Name |
Information |
| PC-25228 |
Grazoprevir
HCV NS3/4A inhibitor
|
Grazoprevir (MK-5172) is a potent, selective inhibitor of HCV NS3/4A protease with broad activity across genotypes and resistant variants, with Ki values of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively, also inhibits SARS-CoV-2 3CLpro activity. |
| PC-24161 |
Netanasvir phosphate
HCV NS5A inhibitor
|
Netanasvir phosphate is a potent, selective fused bicyclic inhibitor of HCV NS5A. |
| PC-24160 |
Netanasvir
HCV NS5A inhibitor
|
Netanasvir is a potent, selective fused bicyclic inhibitor of HCV NS5A. |
| PC-24131 |
Encofosbuvir
HCV NS5B inhibitor
|
Encofosbuvir is a potent inhibitor of HCV NS5B polymerases and inhibitor for HCV replication. |
| PC-24071 |
ML283
HCV NS3 helicase inhibitor
|
ML283 is a potent, specific inhibitor of HCV non-structural protein 3 (NS3) helicase with IC50 of 2.6 uM (HCV genotype 1b), also inhibits DENV NS3-catalyzed RNA unwinding, also is a potent SARS-CoV-2 nsp13 helicase inhibitor. |
| PC-23934 |
Furaprevir
HCV NS3/4A inhibitor
|
Furaprevir (TG-2349) is a potent, highly selective hepatitis C virus NS3/4A protease inhibitor. |
| PC-22913 |
Coblopasvir dihydrochloride
HCV NS5A inhibitor
|
Coblopasvir (KW136, KW-136) dihydrochloride is a novel HCV NS5A inhibitor under development for treatment of HCV infection. |
| PC-21356 |
Sofosbuvir
HCV NS5B inhibitor
|
Sofosbuvir (GS-7977, PSI-7977) is a prodrug of 2'-F-2'-C-methyluridine monophosphate and HCV NS5B polymerase inhibitor, is active against GT 1a, 1b, and 2a (strain JFH-1) replicons and chimeric replicons containing GT 2a (strain J6), 2b, and 3a NS5B polymerase. |
| PC-21355 |
Dasabuvir
HCV NS5B inhibitor
|
Dasabuvir (ABT-333) is a potent, selective, and nonnucleoside inhibitor of HCV NS5B polymerase with IC50 of 2.2-10.7 nM for HCV genotype 1a and 1b. |
| PC-21352 |
Ombitasvir
HCV NS5A inhibitor
|
Ombitasvir (ABT-267) is a potent, selective pan-genotypic inhibitor of HCV NS5A with EC50 of 1.7-19.3 pM against GT1a, -1b, -2a, -2b, -3a, -4a, and -5a and 366 pM against GT6a. |
| PC-63572 |
Beclabuvir hydrochloride
|
Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively. |
| PC-45986 |
Nucleoside-Analog-2
|
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
