| Cat. No. |
Product Name |
Information |
| PC-61888 |
Filibuvir
HCV NS5B inhibitor
|
Filibuvir (PF-00868554, PF-868554) is a nonnucleoside, potent and selective, orally available HCV NS5B inhibitor with IC50 of 19 nM, EC50 of 75 nM (genotype 1b-Con1 replicon). |
| PC-61873 |
Ravidasvir dihydrochloride
HCV NS5A inhibitor
|
Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay. |
| PC-61872 |
Ravidasvir
HCV NS5A inhibitor
|
Ravidasvir (PPI-668, BI 238630) is a potent pan-genotypic HCV NS5A inhibitor with IC50 of 0.12/0.01/1.14 nM for HCV gt-1a/1b/3a in replicon luciferase assay. |
| PC-61524 |
Samatasvir
HCV NS5A inhibitor
|
Samatasvir (IDX719) is a highly potent, selective inhibitor of HCV NS5A that effectively inhibits HCV genotype 1-5 replicons with EC50 of 2-24 pM. |
| PC-61523 |
TD-6450
HCV NS5A inhibitor
|
TD-6450 is a next generation, potent HCV NS5A inhibitor that has potent antiviral activity against HCV infection. |
| PC-61440 |
Voxilaprevir
HCV NS3/4A inhibitor
|
Voxilaprevir (GS-9857) is a potent HCV NS3/4A protease inhibitor, inhibits genotype 1b and 3a wild-type NS3 proteases with Ki values of 0.038 nM and 0.066 nM, respectively. |
| PC-61414 |
Uprifosbuvir
HCV NS5B inhibitor
|
Uprifosbuvir (MK-3682, IDX 21437) is a novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir. |
| PC-60953 |
Faldaprevir
HCV NS3/4A inhibitor
|
Faldaprevir (BI-201335) is a potent, selective noncovalent competitive inhibitor of HCV NS3/4A protease with Ki of 2.6 and 2.0 nM for GT1a and 1b NS3-NS4A protease, respectively. |
| PC-60952 |
Deleobuvir
HCV NS5B inhibitor
|
Deleobuvir (BI-207127, BI207127) is a potent, selective HCV NS5B polymerase inhibitor with IC50 of 50 nM against GT-1 HCV polymerase activity. |
| PC-60429 |
MK-8876
HCV NS5B inhibitor
|
MK-8876 is a broadly acting non-nucleoside inhibitor of HCV NS5B polymerase with IC50 of 3 nM and 2 nM for GT1b and GT2a, respectively.. |
| PC-60428 |
GSK-2485852
HCV NS5B inhibitor
|
GSK-2485852 (GSK2485852, GSK5852) is a highly potent, selective HCV NS5B polymerase inhibitor with IC50 of 3.0 and 1.6 nM for HCV genotypes 1a and 1b in replicon assay, respectively. |
| PC-60427 |
BMS-929075
HCV NS5B inhibitor
|
A highly potent, selective, orally bioavailable HCV NS5B polymerase inhibitor with IC50 of 9, 4, and 18 nM for GT1a, GT1b, and GT1b-C316N mutant in HCV replicon assay, respectively. |
