Uprifosbuvir (MK-3682, IDX 21437)

Chemical Structure : Uprifosbuvir

CAS No.: 1496551-77-9

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货号: PC-61414Not For Human Use, Lab Use Only.

Uprifosbuvir (MK-3682, IDX 21437) is a novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
50 mg		Get quote
100 mg		Get quote

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Uprifosbuvir (MK-3682, IDX 21437) is a novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.

物理化学性质&存储条件

分子量	545.91
分子式	C22H29ClN3O9P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Propan-2-yl (2R)-2-{[(R)-({(2R,3R,4R,5R)-4-chloro-5-[2,4-dioxo-3,4dihydropyrimidin-1(2H)-yl]-3-hydroxy-4-methyloxolan-2yl}methoxy)(phenoxy)phosphoryl]amino}propanoate

参考文献

1. Wyles D, et al. Hepatology. 2017 Jul 7. doi: 10.1002/hep.29358.

2. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Aug 9. pii: S2468-1253(17)30163-2.