| Cat. No. |
Product Name |
Information |
| PC-42480 |
Simeprevir
HCV NS3/4A inhibitor
|
Simeprevir (TMC435, TMC435350) is a potent, orally available inhibitor of HCV NS3/4A protease with Ki of 0.36 nM, replicon EC50 of 7.8 nM. |
| PC-42478 |
Danoprevir
HCV NS3/4A inhibitor
|
Danoprevir (ITMN-191, R-7227) is a potent, highly selective, orally available, peptidomimetic HCV NS3/4A protease inhibitor with IC50 of 0.2-0.4 nM (GT1a, 1b, 4, 5 and 6), 1.6 nM (GT2b). |
| PC-42722 |
RO-9187
HCV NS5B inhibitor
|
RO-9187 is a potent HCV NS5B RNA polymerase inhibitor, inhibits HCV replication in the replicon system with IC50 of 171 nM. |
| PC-42604 |
Daclatasvir
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
| PC-42603 |
Daclatasvir dihydrochloride
HCV NS5A inhibitor
|
Daclatasvir (BMS-790052) dihydrochloride is a potent HCV NS5A inhibitor with EC50 of <50 pM against genotype 1 replicons. |
| PC-45961 |
Lomibuvir
HCV NS5B inhibitor
|
Lomibuvir (VX-222, VCH-222) is a potent and selective, nonnucleoside inhibitor of HCV NS5B polymerase inhibitor with Kd of 17 nM. |
| PC-42605 |
NM107
HCV NS5B inhibitor
|
NM107 (Valopicitabine) is a nucleoside inhibitor of HCV NS5B polymerase with EC50 of 1.23 uM against HCV 1b replicon cells. |
| PC-42023 |
Peretinoin
|
Peretinoin (NIK333) is an orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities. |
| PC-42646 |
Tegobuvir
HCV NS5B inhibitor
|
Tegobuvir (GS-333126, GS-9190) is a nonnucleoside inhibitor of HCV NS5B polymerase that acts as a potent inhibitor of HCV genotype 1. |
| PC-45985 |
Nucleoside-Analog-1
|
A 4′-azidocytidine analogue that shows anti-HCV activity.. |
| PC-26092 |
VCH-916
HCV NS5B inhibitor
|
VCH-916 is a potent, selective inhibitor of HCV NS5B (non-nucleoside-type) polymerase inhibitor. |
| PC-25230 |
Asunaprevir
HCV NS3 inhibitor
|
Asunaprevir (BMS-650032) is a potent and orally bioavailable hepatitis C virus (HCV) NS3 protease inhibitor with IC50 of 0.2-3.5 nM, also inhibits SARS-CoV-2 3CLpro activity. |
