E3 Ubiquitin Ligase (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofE3 Ubiquitin Ligase E3 Ubiquitin Ligase

Cat. No.	Product Name	Information
PC-21790	MN551 SOCS2 inhibitor	MN551 is a Cys111-specific, covalent ligand targeting the E3 ligase SOCS2 with ITC Ki value of 2.2 uM, blocks recruitment of cellular SOCS2 protein to its native substrate.
PC-21555	C7683 Cbl-b inhibitor	C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.
PC-21307	Smurf1 inhibitor 1 SMURF1 inhibitor	Smurf1 inhibitor 1 is a potent, selective Smurf1 E3 ligase inhibitor with IC50 of 230 nM in in UbFluor assays, inhibits the catalytic HECT domain of Smurf1.
PC-20919	SMURF1 inhibitor 29 SMURF1 inhibitor	SMURF1 inhibitor 29 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 11 nM, displays no activity against SMURF2.
PC-20904	SMURF1 inhibitor 38 SMURF1 inhibitor	SMURF1 inhibitor 38 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 92 nM, displays no activity against SMURF2.

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