| Cat. No. |
Product Name |
Information |
| PC-28050 |
Muvadenant fumarate
Adenosine A2A/A2B inhibitor
|
Muvadenant fumarate (M1069) is a potent, orally active dual antagonist of the A2A and A2B adenosine receptors, with selectivity of >100 fold against the A1 and A3 receptors. |
| PC-27083 |
JNJ-10450232
A3AR agonist
|
JNJ-10450232 (NTM-006) is a structural analog of acetaminophen, non-opioid, non-NSAID analgesic and antipyretic compound, demonstrates anti-pyretic and/or analgesic activities, NTM-006 is a selective adenosine A3 receptor (A3AR) agonist. |
| PC-25759 |
P626
A2AR/A2BR antagonist
|
P626 is a potent, selective dual adenosine A2A/A2B receptor (A2AR/A2BR) antagonist with IC50 of 5.73 nM and 34 nM at both hA2AAR and hA2BAR (cAMP assay), with no significant acitivity against hA1AR and hA3AR. |
| PC-23909 |
FM101
A3AR inhibitor
|
FM101 (LJ-2698) is a highly potent and selective antagonist of A3 adenosine receptor (A3AR), selectively binds to human A3AR with Ki of 1.44 nM. |
| PC-23389 |
SLV320
A1AR antagonist
|
Derenofylline (SLV320) is a potent, selective and orally active adenosine A1 receptor (A1AR) antagonist with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. |
| PC-22840 |
DPCPX
A1AR antagonist
|
DPCPX (PD116948) is a highly potent and selective adenosine A1 receptor antagonist with Ki of 0.46 nM, >500-fold selective over A2 receptor. |
| PC-22524 |
MRS1754
A2BR antagonist
|
MRS1754 (MRS-1754) is a potent, adenosine receptor A2B adenosine receptor (A2BAR) selective antagonist with Ki of 1.97 nM, 205-, 255-, and 289-fold selective for the human A2BARs vs. human A1/A2A/A3 ARs, respectively. |
| PC-22193 |
Piclidenoson
A3AR agonist
|
Piclidenoson (IB-MECA, CF101) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist, shows antiproliferative effect and induces apoptosis in multiple cancer cell types like melanoma, leukemia. |
| PC-22013 |
CVT-6694
A2BR antagonist
|
CVT-6694 (CVT6694) is a highly potent, selective A2B adenosine receptor antagonist with Ki of 7 nM (hA2B), >700-fold selective over human A1, A2A and A3 receptors. |
| PC-21513 |
TRR469
A1AR modulator
|
TRR469 is a potent, selective adenosine A1 receptor (A1AR) positive allosteric modulator with pKb of 5.36, exhibits anti-nociceptive properties in acute and neuropathic pain models in mice. |
| PC-21512 |
VCP171
A1AR PAM
|
VCP171 is a selective adenosine A1 receptor (A1AR) positive allosteric modulator (PAM), inhibits eEPSC amplitude of nerve-injury versus control animals in both lamina I and lamina II neurons. |
| PC-21510 |
MRS7935
A1AR modulator
|
MRS7935 is a potent, selective positive allosteric modulator (PAM) of A1 adenosine receptor (A1AR) with EC50 of 1.43 uM. |
