| Cat. No. |
Product Name |
Information |
| PC-43811 |
ZCL278
Cdc42 inhibitor
|
ZCL278 is a potent, cell-permeable Cdc42-specific small-molecule inhibitor (Kd=6.4 uM). |
| PC-27402 |
Acmiribine
Rac1 inhibitor
|
Acmiribine (8-Hydroxy-2-deoxyguanosine, 8-OHdG) is a small molecule Rac1 inhibitor, suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia. |
| PC-26767 |
(R)-Ketorolac
Cdc42/Rac1 inhibitor
|
(R)-Ketorolac (R-ketorolac) is a small molecule allosteric Cdc42 and Rac1 GTPases inhibitor, significantly inhibits cell adhesion, migration and invasion in ovarian cancer cells. |
| PC-26551 |
Ran inhibitor M36
RAN GTPase inhibitor
|
Ran inhibitor M36 (Ran-IN-1) is a specific small molecule inhibitor of Ran GTPase, inhibits Ran-GTP activation, has IC50 of 10.02 uM in clonogenic assays for TOV112D cell line. |
| PC-25791 |
(6R)-HR3119
RhoGDI2 inhibitor
|
(6R)-HR3119 is a small molecule ligand of Guanine nucleotide dissociation inhibitors (GDIs) protein RhoGDI2 with low-micromolar affinity (Kd= 4 uM), engages with RhoGDI2 in cells and suppresses the migration of aggressive breast cancer cells. |
| PC-25187 |
Rac1 Inhibitor W56
RAC1 inhibitor
|
Rac1 Inhibitor W56 is a peptide inhibitor of Rac1 containing residues 45-60 of Rac1, inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam. |
| PC-24534 |
MLS-573151
Cdc42 inhibitor
|
MLS-573151 (MLS000573151) is a specific small molecule inhibitor of GTPase Cdc42 with EC50 of 2 uM, selective over other Rho family GTPases, including Rac1, Rac 2, RhoA. |
