Immune Checkpoints (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofImmune Checkpoints Immune Checkpoints

Cat. No.	Product Name	Information
PC-38146	VISTA inhibitor III VISTA inhibitor	VISTA inhibitor III is a small-molecule ligand for immune checkpoint VISTA with IC50 of 480 nM in FRET assay.
PC-38145	NSC622608 VISTA inhibitor	NSC622608 (NSC 622608) is the first small-molecule ligand for immune checkpoint VISTA with IC50 of 4.8 uM in FRET assay.
PC-35927	RRx-001 CD47-SIRPα inhibitor	RRx-001 (RRx001) is a novel NO and hypoxia mediated anticancer agent with with epigenetic and immunologic activity, RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α.
PC-62015	DRI-C21045 CD40-CD40L inhibitor	DRI-C21045 is a novel small-molecule inhibitor of CD40-CD40L protein-protein interaction with IC50 of 0.17 uM in cell-based assays.
PC-27783	5-OE-RU MR1 ligand, MAIT cell antigen	5-OE-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.
PC-27782	5-OP-RU MR1 ligand, MAIT cell antigen	5-OP-RU is a natural product formed during bacterial synthesis of vitamin B2, potently activates mucosal associated invariant T (MAIT) cells and has immunomodulatory, inflammatory, and anticancer properties, binds to histocompatibility complex (MHC)-related protein MR1.

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