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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Immune Checkpoints-L557-0155
L557-0155

Chemical Structure : L557-0155

CAS No.: 1115893-25-8

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L557-0155 (L 557-0155)

货号: PC-38587Not For Human Use, Lab Use Only.

L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.

规格 价格 库存 数量
2 mg ￥2480 In stock
5 mg ￥3980 In stock
10 mg ￥5880 In stock
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纯度 & COA & 质检文件 纯度: 99.9% (HPLC) Select Batch:

生物&药学活性

L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.

物理化学性质&存储条件

分子量 422.869
分子式 C22H19ClN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl)-3-(3,5-dimethoxyphenyl)urea

参考文献

1. Wenting Chen, et al. Invest New Drugs. 2022 Apr 11. doi: 10.1007/s10637-022-01244-4.

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