| Cat. No. |
Product Name |
Information |
| PC-26094 |
Ro24-7429
HIV-1 Tat inhibitor, RUNX1 inhibitor
|
Ro24-7429 is a potent, specific and orally active HIV-1 transactivator protein Tat antagonist, is also a runt-related transcription factor 1 (RUNX1) inhibitor. |
| PC-26025 |
Fosamprenavir
HIV-1 protease inhibitor
|
Fosamprenavir (Amprenavir phosphate, GW433908) is the phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility. |
| PC-25848 |
019854-B06
HIV-1 Tat inhibitor
|
019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide. |
| PC-25467 |
Fostemsavir
HIV-1 attachment inhibitor
|
Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of Temsavir (BMS-626529), which is a highly potent, small molecule HIV-1 attachment inhibitor, inhibits HIV-1 gp120-directed attachment by preventing gp120 from binding to CD4. |
| PC-25440 |
VH4011499
HIV-1 capsid inhibitor
|
VH4011499 (VH-499) is a highly potent HIV-1 capsid inhibitor with EC50 and EC90 of 0.023 nM and 0.061 nM respectively. |
| PC-25439 |
VH4004280
HIV-1 capsid inhibitor
|
VH4004280 (VH-280) is a highly potent HIV-1 capsid inhibitor with EC50 and EC90 of 0.093 nM and 0.23 nM respectively. |
| PC-25108 |
Cyclotriazadisulfonamide
Sec61 inhibitor
|
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor. |
| PC-25061 |
Lepetegravir
HIV-1 integrase inhibitor
|
Lepetegravir is a potent HIV-1 integrase inhibitor, inhibits the replication of HIV-I (IIIB) in MT-4 cells. |
| PC-25032 |
Asuptegravir
HIV-1 integrase inhibitor
|
Asuptegravir is a potent, selective HIV integrase inhibitor. |
| PC-25019 |
Suricapavir
HIV-1 integrase inhibitor
|
Suricapavir is a potent, selective HIV-1 integrase inhibitor. |
| PC-24825 |
BIT225
HIV-1 Vpu inhibitor
|
BIT225 (BIT-225) is a specific small molecule inhibitor of HIV-1 Vpu ion channel activity, inhibits the release of HIV-1 in human MDM with EC50 of 2.25 uM. |
| PC-24720 |
NNRTI compound 5i3
NNRTI
|
NNRTI compound 5i3 is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), shows potent antiviral activity against NNRTI-resistant strains (GH9, p1579, p5375, p1833, and p5735) with EC50 of 2.6-18.3 nM. |
