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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-Cyclotriazadisulfonamide
Cyclotriazadisulfonamide

Chemical Structure : Cyclotriazadisulfonamide

CAS No.: 182316-44-5

Cyclotriazadisulfonamide (CADA)

货号: PC-25108Not For Human Use, Lab Use Only.

Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor.

物理化学性质&存储条件

分子量 581.79
分子式 C31H39N3O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

9-Benzyl-3-methylene-1,5-ditosyl-1,5,9-triazacyclododecane

参考文献

1. Victor Van Puyenbroeck, et al. Traffic. 2020 Feb;21(2):250-264.

2. Kurt Vermeire, et al. Curr HIV Res. 2008 May;6(3):246-56.

3. Pauwels E, et al. Int J Mol Sci. 2021 Nov 5;22(21):12007.

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