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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-Fostemsavir
Fostemsavir

Chemical Structure : Fostemsavir

CAS No.: 864953-29-7

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Fostemsavir (BMS-663068)

货号: PC-25467Not For Human Use, Lab Use Only.

Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of Temsavir (BMS-626529), which is a highly potent, small molecule HIV-1 attachment inhibitor, inhibits HIV-1 gp120-directed attachment by preventing gp120 from binding to CD4.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of Temsavir (BMS-626529), which is a highly potent, small molecule HIV-1 attachment inhibitor, inhibits HIV-1 gp120-directed attachment by preventing gp120 from binding to CD4.

物理化学性质&存储条件

分子量 583.50
分子式 C25H26N7O8P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3-(2-(4-Benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-1-yl)methyl dihydrogen phosphate

参考文献

1. Zhou N, et al. J Antimicrob Chemother. 2014 Mar;69(3):573-81.

2. Li Z, et al. Antimicrob Agents Chemother. 2013 Sep;57(9):4172-80.

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