| Cat. No. |
Product Name |
Information |
| PC-61160 |
AA-CW236
MGMT inhibitor
|
AA-CW236 is a potent, selective, non-pseudosubstrate inhibitor of O(6) -alkylguanine DNA methyltransferase (MGMT) with low-nanomolar potency. |
| PC-60765 |
SGI-110
DNMT inhibitor
|
SGI-110 (Guadecitabine) is a novel DNA hypomethylating dinucleotide that inhibits DNA methyltransferase (DNMT). |
| PC-43810 |
SGI-1027
DNMT inhibitor
|
SGI-1027 (SGI1027) is a potent inhibitor of DNA methyltransferase (DNMT) with IC50s of 6-12.5 uM for DNMT1, DNMT3A, and DNMT3B. |
| PC-28370 |
Procainamide hydrochloride
DNMT inhibitor
|
Procainamide hydrochloride (Procaine amide, SP100) is a competitive DNA methyltransferase (DNMT) inhibitor, reactivates the expression of tumor suppressor factors by demethylating tumor suppressor genes, induces vacuolization in various cell types and reduces cell proliferation and migration. |
| PC-28369 |
Procainamide
DNMT inhibitor
|
Procainamide (Procaine amide, SP100) is a competitive DNA methyltransferase (DNMT) inhibitor, reactivates the expression of tumor suppressor factors by demethylating tumor suppressor genes, induces vacuolization in various cell types and reduces cell proliferation and migration. |
| PC-28368 |
Hydralazine hydrochloride
DNMT inhibitor
|
Hydralazine hydrochloride is an orally active, blood-brain barrier-permeable DNA methyltransferase (DNMT) inhibitor, shows vasodilatory, arterial smooth muscle relaxant and hypotensive activities, also shows neuroprotective and anti-inflammatory properties. |
| PC-28367 |
Hydralazine
DNMT inhibitor
|
Hydralazine is an orally active, blood-brain barrier-permeable DNA methyltransferase (DNMT) inhibitor, shows vasodilatory, arterial smooth muscle relaxant and hypotensive activities, also shows neuroprotective and anti-inflammatory properties. |
| PC-27598 |
Decitabine
DNMT inhibitor
|
Decitabine (5-Aza-2'-deoxycytidine, 5-AZA-CdR) is an orally active deoxycytidine analogue antimetabolite and DNA methyltransferase (DNMT) inhibitor, incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme, induces cell G2/M arrest and cell apoptosis. |
| PC-26866 |
Nanaomycin A
DNMT3B inhibitor
|
Nanaomycin A is a quinone antibiotics and selective DNA methyltransferase DNMT3B inhibitor with IC50 of 500 nM. |
