| Cat. No. |
Product Name |
Information |
| PC-24395 |
SCM-01
CYP3A4 inhibitor
|
SCM-01 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.32 uM in P450-Glo inhibition assays, 14-fold selecitve over CYP3A5. |
| PC-24049 |
Vicadrostat
Aldosterone synthase inhibitor
|
Vicadrostat (BI 690517) is a potent, highly selective aldosterone synthase (AS) inhibitor with IC50 of 48 nM, 250-fold selectivity for aldosterone synthase compared with cortisol synthase. |
| PC-23938 |
Ketoconazole
CYP3A4 inhibitor
|
Ketoconazole (R 41400) is an imidazole anti-fungal agent and CYP3A4 and CYP24A1 inhibitor. |
| PC-23802 |
CYP3cide
CYP3A4 inhibitor
|
CYP3cide (PF-04981517) is a potent, efficient, and specific time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) with IC50 of 0.03 uM, >500-fold selective over CYP3A5 and CYP3A7. |
| PC-23328 |
CYP4A11 and CYP4F2 inhibitor 15
CYP4A11/4F2 inhibitor
|
CYP4A11 and CYP4F2 inhibitor 15 is a potent, dual inhibitor of cytochrome P450 (CYP) 4F2 and CYP4A11 (CYP4A11/4F2) with IC50 of 120/220 nM respectively, exhibits potent suppression of 20-HETE production in both human and rat renal microsomes with IC50 of 18 nM and 37 nM. |
| PC-23290 |
CYP2E1 inhibitor Q11
CYP2E1 inhibitor
|
CYP2E1 inhibitor Q11 is a specific Cytochrome P450 2E1 (CYP2E1) inhibitor with Ki of 897 nM. |
| PC-21449 |
Dual CYP19A1/CYP11B2 inhibitor X21
CYP19A1/CYP11B2 inhibitor
|
Dual CYP19A1/CYP11B2 inhibitor X21 is a potent and selective dual inhibitor of aromatase (CYP19A1) and aldosterone synthase (CYP11B2) with IC50 of 2.3 nM and 29 nM, respectively. |
| PC-21418 |
TPP-IOA
Cyt c peroxidase inhibitor
|
TPP-IOA is a specific inhibitor of cytochrome c (cyt c) peroxidase activity, inhibits peroxidase activity of cardiolipin-induced cytochrome c peroxidase activity with IC50 of 5 uM. |
| PC-20707 |
TP0472993
20-HETE synthesis inhibitor
|
TP0472993 is a potent, selective 20-Hydroxyeicosatetraenoic acid (20-HETE) synthesis inhibitor, inhibits 20-HETE formation in human and rat renal microsomes with IC50 of 29 and 347 nM, respectively. |
| PC-49301 |
BMS-737
CYP17 lyase inhibitor
|
BMS-737 (BMS737) is a potent, , selective, non-steroidal, reversible inhibitor of CYP17 lyase, 11-fold selectivity for CYP17 lyase over CYP17 hydroxylase. |
