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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cytochrome P450 (CYPs)-CYP4Z1-IN-1
CYP4Z1-IN-1

Chemical Structure : CYP4Z1-IN-1

CAS No.: 2760611-38-7

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CYP4Z1-IN-1 (Compound 7c)

货号: PC-26843Not For Human Use, Lab Use Only.

CYP4Z1-IN-1 (Compound 7c) is a potent, selective CYP4Z1 inhibitor with IC50 of 41.8 nM, >30-fold selective over CYP4F12, decreases the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in breast cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CYP4Z1-IN-1 (Compound 7c) is a potent, selective CYP4Z1 inhibitor with IC50 of 41.8 nM, >30-fold selective over CYP4F12, decreases the expression of stemness markers, spheroid formation, and metastatic ability as well as tumor-initiation capability in breast cancer cells.

物理化学性质&存储条件

分子量 250.30
分子式 C13H18N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

ethyl (E)-4-(4-(((hydroxyamino)methylene)amino)phenyl)butanoate

参考文献

1. Yuan Y, et al. J Med Chem. 2022 Dec 8;65(23):15749-15769.

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