| Cat. No. |
Product Name |
Information |
| PC-70026 |
CPI-268456
BRD4 inhibitor
|
CPI-268456 is a small molecule ligand of bromodomain-containing protein 4 (BRD4), binds to BRD4 with IC50 of 0.5 uM in cell-free assays. |
| PC-60022 |
BAY-850
ATAD2 inhibitor
|
BAY-850 (BAY 850, BAY850) is a potent, isoform selective, cellularly active ATAD2 bromodomain inhibitor with binding IC50 of 166 nM in TR-FRET assay. |
| PC-45582 |
I-BRD9
BRD9 inhibitor
|
I-BRD9 is the first selective cellular chemical probe inhibitor for BRD9 with pIC50 of 7.3. |
| PC-45508 |
GSK-5959
BRPF1 inhibitor
|
GSK-5959 (GSK5959) is the first potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.1. |
| PC-45994 |
JQ-1 carboxylic acid
BET inhibitor
|
JQ-1 carboxylic acid is an inhibitor of bromodomain and extra terminal domain (BET) family proteins with Kd of 128, 59.5, 49.0, and 190 nM for JQ1 binding to bromodomains of BRD2, BRD3, BRD4, and BRDT, respectively, blocking their interaction with acetylated histones. |
| PC-42110 |
BI-9564
BRD9 inhibitor
|
BI-9564 (BI9564) is a potent, selective, cell-permeable and noncytotoxic BRD9 bromodomain inhibitor with IC50 of 75 nM, Kd of <20 nM. |
| PC-42220 |
AZD5153 6-Hydroxy-2-naphthoic acid
BRD4 bromodomain inhibitor
|
AZD5153 is a potent, selective, bivalent and orally available BET/BRD4 bromodomain with IC50 of 5 nM. |
| PC-45507 |
PFI-4
BRPF1 inhibitor
|
PFI-4 is a potent, selective inhibitor of the BRPF1 bromodomain with pIC50 of 7.3. |
| PC-42109 |
BI-7273
BRD9 inhibitor
|
BI-7273 is a potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay. |
| PC-45780 |
PF-CBP1 hydrochloride
CBP/p300 inhibitor
|
PF-CBP1 hydrochloride is a potent, highly selective inhibitor of the CBP and p300 bromodomains with IC50 of 125 nM and 363 nM, respectively. |
| PC-42090 |
GSK6853
BRPF1 inhibitor
|
GSK6853 (GSK-6853) is a potent, highly selective and cell-active BRPF1 bromodomain inhibitor with TR-FRET pIC50 of 8.1. |
| PC-42168 |
CPI-637
CBP/p300 inhibitor
|
CPI-637 is a potent and selective, cell-active CBP/EP300 bromodomain inhibitor with CBP BRET EC50 of 0.03 uM. |
