Neuropeptide Y Receptor (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-26157	NN501 GPR10/NPFFR2 agonist	NN501 (NN0489-0501) is a potent, dual-acting pepetide agonist of GPR10 and neuropeptide FF receptor 2 (NPFFR2) with EC50 of 0.7 nM and 9.1 nM for hGPR10 and hNPFFR2 respecitvely.
PC-26144	BMS-193885 Y1R antagonist	BMS-193885 is a potent, selective neuropeptide Y(1) receptor (Y1R) antagonist with binding Ki of 3.3 nM, demonstrates full functional antagonism with Kb of 4.54 nM in forskolin-stimulated c-AMP production assay using CHO cells expressing human Y(1) receptor.
PC-26143	Y2R antagonist SF-11 Y2R antagonist	Y2R antagonist SF-11 is potent, selective and brain penetrant antagonist of Neuropeptide Y Y2 Receptor (Y2R) with IC50 of 199 nM, induces antidepressant-like effect in rats.
PC-23613	Hederagenin NPFFR1 antagonist	Hederagenin is a triterpenoid saponin with antitumor activity against multifarious cancers, is a selective antagonist of neuropeptide FF receptor 1 (NPFFR1), selectively inhibits activation of NPFFR1 by NPFF or NPVF through orthosteric antagonism.

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