| Cat. No. |
Product Name |
Information |
| PC-25726 |
Pargyline
MAO inhibitor
|
Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Ki of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively, also is a modest PYCR1 inhibitor, inhibits the formation of proline in human breast cancer cells. |
| PC-25717 |
PQM-244
MAO-B inhibitor
|
PQM-244 is a selective MAO-B inhibitor with IC50 of 4.17 uM with non-competitive inhibition mechanism (Ki=2.28 uM), shows significant peripheral and central antinociceptive effects. |
| PC-25617 |
MBA-159
MAO/AChE inhibitor
|
MBA-159 is a multitarget small molecule inhibitor of monoamine oxidases (MAOs) and cholinesterases (ChEs) with IC50 of 28.8 uM and 53.8 uM for hMAO-A and hAChE respectively, demonstrates anti-amnesic properties and significantly improved non-spatial memory in mouse model of scopolamine-induced amnesia. |
| PC-23801 |
RG0216
MAO-B inhibitor
|
RG0216 is a potent, selective and reversible monoamine oxidase (MAO-B) inhibitor, >260-fold selectivity over MAO-A. |
| PC-22456 |
XYY-CP1106
Iron chelator/MAO-B inhibitor
|
XYY-CP1106 is a multi-targeted candidate in Alzheimer's disease (AD) with dual-property of iron chelation (Fe3+ chelation, pFe3+ = 18.04) and monoamine oxidase B inhibition (MAO-B, IC50=14.7 nM). |
| PC-60502 |
Sercloremine hydrochloride
|
A selective, reversible inhibitor of MAO-A and serotonin reuptake inhibitor as an antidepressant.. |