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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Monoamine Oxidase (MAO)-PQM-244
PQM-244

Chemical Structure : PQM-244

CAS No.:

PQM-244 (PQM244)

货号: PC-25717Not For Human Use, Lab Use Only.

PQM-244 is a selective MAO-B inhibitor with IC50 of 4.17 uM with non-competitive inhibition mechanism (Ki=2.28 uM), shows significant peripheral and central antinociceptive effects.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

PQM-244 is a selective Monoamine oxidase B (MAO-B) inhibitor with IC50 of 4.17 uM with non-competitive inhibition mechanism (Ki=2.28 uM), shows significant peripheral and central antinociceptive effects.

物理化学性质&存储条件

分子量 298.39
分子式 C18H22N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S,E)-4-methoxy-N’-(2-methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ylidene)benzohydrazide

参考文献

1. Dos Reis Rosa Franco G, et al. Future Med Chem. 2025 Jun;17(11):1229-1240.

2. Dos Reis VEN, et al. J Pharm Biomed Anal. 2025 Oct 15;268:117200.

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