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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Monoamine Oxidase (MAO)-Pargyline
Pargyline

Chemical Structure : Pargyline

CAS No.: 555-57-7

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Pargyline

货号: PC-25726Not For Human Use, Lab Use Only.

Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Ki of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively, also is a modest PYCR1 inhibitor, inhibits the formation of proline in human breast cancer cells.

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1 g ￥380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Ki of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively, also is a modest PYCR1 inhibitor, inhibits the formation of proline in human breast cancer cells.

物理化学性质&存储条件

分子量 159.23
分子式 C11H13N
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-Benzyl-N-methylprop-2-yn-1-amine

参考文献

1. C J Fowler, et al. Biochem Pharmacol. 1982 Nov 15;31(22):3555-61.

2. Kirsty Milne, et al. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2626-2631.

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