Microsomal Triglyceride Transfer Protein (MTP) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-63288	PF-02575799 MTP inhibitor	PF-02575799 is a highly potent microsomal triglyceride transfer protein (MTP) inhibitor with IC50 of 0.77 nM.
PC-60675	CP-346086 MTP inhibitor	CP-346086 is a potent, orally active microsomal triglyceride transfer protein (MTP) inhibitor that inhibits both human and rodent MTP with IC50 of 2 nM.
PC-60674	SLx-4090 MTP inhibitor	SLx-4090 (KD-026) is a novel potent, selective and orally active enterocytic microsomal triglyceride transfer protein (MTP) inhibitor that inhibits only MTP localized to enterocytes with IC50 of 6 nM.
PC-24772	Lomitapide MTP inhibitor	Lomitapide (AEGR-733, BMS-201038) is a highly potent inhibitor of microsomal triglyceride-transfer protein (MTP), inhibits triglyceride transfer of human MTP in vitro with IC50 of 0.5 nM, inhibits secretion of apoB from HepG2 cells with IC50 of 0.8 nM.
PC-24765	Dirlotapide MTP inhibitor	Dirlotapide (CP742033) is a potent inhibito rof microsomal triglyceride transfer protein (MTP), inhibits Apo B secretion from human HepG2 cells and in canine hepatocytes with IC50 of 1.5 nM and 2.9 nM respectively.
PC-24764	Granotapide MTP inhibitor	Granotapide (JTT-130) is a potent, intestine-specific, orally active inhibitor of microsomal triglyceride transfer protein (MTP), reduces absorption of cholesterol and triglycerides through inhibition of MTP.

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