| Cat. No. |
Product Name |
Information |
| PC-72741 |
MRGPRX1 inhibitor 1t
MRGPRX1 modulator
|
MRGPRX1 inhibitor 1t is a potent, selective, positive allosteric modulator (PAM) of Mas-related G protein-coupled receptor X1 (MRGPRX1) with EC50 of 0.1 uM. |
| PC-38069 |
MS47134
MRGPRX4 agonist
|
MS47134 is a potent, selective MRGPRX4 agonist with EC50 of 149 nM. |
| PC-38068 |
MRGPRX2 antagonist C9
MRGPRX2 inhibitor
|
MRGPRX2 antagonist C9 is a potent and selective MRGPRX2 inverse agonist (antagonist) with Ki of 43 nM. |
| PC-38067 |
ZINC16991592
MRGPRX2 inhibitor
|
ZINC16991592 (ZINC1592) is a selective MRGPRX2 antagonist with Ki of 189 nM. |
| PC-38066 |
MRGPRX1 agonist 1
MRGPRX1 agonist
|
MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors. |
| PC-62228 |
ZINC-3573 racemate
MRGPRX2 agonist
|
ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases. |
| PC-62227 |
(R)-ZINC-3573
MRGPRX2 agonist
|
(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases. |
| PC-27051 |
INCB000262
MRGPRX2 antagonist
|
INCB000262 (EP262) is an oral small-molecule Mas-related G-protein-coupled receptor X2 (MRGPRX2) antagonist, inhibits inflammatory disease phenotypes and mast cell-associated transcriptional changes in the HDM+SEB mouse model of AD. |
| PC-24415 |
Cortistatin-14 TFA
MRGPRX2 agonist
|
Cortistatin-14 TFA (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM. |
| PC-24414 |
Cortistatin-14
MRGPRX2 agonist
|
Cortistatin-14 (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM. |
| PC-24411 |
AR244555
Mas inverse agonist
|
AR244555 is a specific, non-peptide inverse agonist of G protein-coupled receptor Mas with IC50 of 186 and 348 nM for human and rat Mas receptor respectively. |
| PC-24183 |
Setomagpran
MRGPRX2 antagonist
|
Setomagpran is a potent, selective antagonist of Mas-related G-protein receptor X2 (MRGPRX2) with anti-inflammatory activity. |
