| Cat. No. |
Product Name |
Information |
| PC-62227 |
(R)-ZINC-3573
MRGPRX2 agonist
|
(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases. |
| PC-24415 |
Cortistatin-14 TFA
MRGPRX2 agonist
|
Cortistatin-14 TFA (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM. |
| PC-24414 |
Cortistatin-14
MRGPRX2 agonist
|
Cortistatin-14 (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM. |
| PC-24413 |
PSB-172656
MRGPRX2 antagonist
|
PSB-172656 is a highly potent, selective non-cytotoxic MAS-related G protein-coupled receptor-X2 (MRGPRX2) antagonist with Ki of 0.142 nM, does not block any of the other MRGPRX subtypes at 10 uM. |
| PC-24412 |
AR234960
Mas agonist
|
AR234960 is a specific, non-peptide agonist of G protein-coupled receptor Mas with IC50 of 351 and 172 nM for human and rat Mas receptor respectively. |
| PC-24411 |
AR244555
Mas inverse agonist
|
AR244555 is a specific, non-peptide inverse agonist of G protein-coupled receptor Mas with IC50 of 186 and 348 nM for human and rat Mas receptor respectively. |
| PC-24183 |
Setomagpran
MRGPRX2 antagonist
|
Setomagpran is a potent, selective antagonist of Mas-related G-protein receptor X2 (MRGPRX2) with anti-inflammatory activity. |
| PC-24159 |
Nelremagpran
MRGPRX4 modulator
|
Nelremagpran is a potent, selective inverse agonist / modulator of Mas-related G-protein receptor X4 (MRGPRX4). |
| PC-23468 |
MRGPRX2 antagonist Compound B
MRGPRX2 antagonist
|
MRGPRX2 antagonist Compound B is a potent, selective MRGPRX2 antagonist with IC50 of 2.9 nM for inhibition of cortistatin 14-mediated MRGPRX2 activation. |
| PC-23467 |
MRGPRX2 antagonist Compound A
MRGPRX2 antagonist
|
MRGPRX2 antagonist Compound A is a potent, selective MRGPRX2 antagonist with IC50 of 50 nM for inhibition of cortistatin 14-mediated MRGPRX2 activation. |
