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首页-小分子抑制剂&激动剂-GPCR-Mas-related G protein-coupled receptor (MRGPR)-INCB000262
INCB000262

Chemical Structure : INCB000262

CAS No.:

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INCB000262 (INCB-000262, EP262, EP-262)

货号: PC-27051Not For Human Use, Lab Use Only.

INCB000262 (EP262) is an oral small-molecule Mas-related G-protein-coupled receptor X2 (MRGPRX2) antagonist, inhibits inflammatory disease phenotypes and mast cell-associated transcriptional changes in the HDM+SEB mouse model of AD.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

INCB000262 (EP262) is an oral small-molecule Mas-related G-protein-coupled receptor X2 (MRGPRX2) antagonist, inhibits inflammatory disease phenotypes and mast cell-associated transcriptional changes in the HDM+SEB mouse model of AD.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Joshua Wollam, et al. J Invest Dermatol. 2026 May 4:S0022-202X(26)01182-6.

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