Cortistatin-14 TFA | MRGPRX2 agonist | Probechem Biochemicals

Chemical Structure : Cortistatin-14 TFA

CAS No.:

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货号: PC-24415Not For Human Use, Lab Use Only.

Cortistatin-14 TFA (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cortistatin-14 TFA (CST-14) is a high affinity endogenous peptide agonist of MRGPRX2 (MrgX2) with EC50 of 25 nM.

分子量	1832.8
分子式	C81H114N20O18S2.xC2HF3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sequence: L-Lysinamide, L-prolyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-seryl-L-seryl-L-cysteinyl-, cyclic (2→13)-disulfide

1. Siehler S, et al. Mol Cell Endocrinol. 2008 May 14;286(1-2):26-34.

2. Ding Y, et al. Int Immunopharmacol. 2023 Apr;117:110003.

3. Robas N, et al. J Biol Chem. 2003 Nov 7;278(45):44400-4.

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