| Cat. No. |
Product Name |
Information |
| PC-27028 |
S961
Insulin receptor antagonist
|
S961 is a selective, high-affinity peptide antagonist of insulin receptor (IR) with IC50 of 0.048 nM and 0.027 nM for human insulin receptor HIR-A and HIR-B respectively, >1000-fold selectivity over human insulin-like growth factor I receptor (IGF-IR). |
| PC-42501 |
BMS-536924
IGF1R/InsR inhibitor
|
BMS-536924 is a potent IGF-1R/InsR inhibitor with IC50 of 100 nM/73 nM, respectively. |
| PC-42046 |
NT-157
InsR inhibitor
|
NT-157 (Tyrphostin NT157) is a potential anti-cancer agent and IGF1R signaling inhibitor that targets insulin receptor substrates IRS1/2 to degradation. |
| PC-23218 |
IR-IGF-1R heterodimer modulator HI-2
IR: IGF-1R hybrid receptor inhibitor
|
HI-2 is a small molecule modulator of insulin receptor-insulin like growth factor-1 receptor heterodimers, inhibits insulin receptor/IGF-1 receptor hybrid formation, with no effects on IR or IGF-1R. |