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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein

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Cat. No. Product Name Information
PC-23728

PFM03

MRE11 inhibitor

PFM03 is a specific MRE11 endonuclease inhibitor, affects DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ).
PC-22774

HDGFRP2 PWWP domain inhibitor BBP

HDGFRP2 PWWP inhibitor

BBP is a small molecule inhibitor of the hepatoma-derived growth factor-related protein 2 (HDGFRP2) PWWP domain, dually targets both HDGFRP2 and PSIP1 PWWP domains, engage with the aromatic cage of the HDGFRP2 PWWP domain.
PC-22697

MUS81 inhibitor 24

MUS81 inhibitor

MUS81 inhibitor 24 is a small molecule inhibitor of DNA repair endonuclease Mus81 with IC50 of 0.27 uM and SPR Kd of 1.1 uM (MUS81-EME1).
PC-20533

MTH1 inhibitor AZ19

MTH1 inhibitor

MTH1 inhibitor AZ19 is a highly potent MTH1 inhibitor with IC50 of 0.9 nM and Kd of 0.5 nM, displays EC50 of 7 nM in whole cell thermal stability assay in K562 cells.

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