| Cat. No. |
Product Name |
Information |
| PC-60774 |
ANI-7
AhR agonist
|
ANI-7 is a potent and selective (up to 263-fold) inhibitor of breast cancer cells with GI50 of 0.5 uM (MCF-7), via activation the aryl hydrocarbon receptor (AhR) pathway. |
| PC-60390 |
GNF-351
AhR antagonist
|
GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential. |
| PC-60054 |
Benvitimod
AhR agonist
|
Benvitimod (GSK-2894512, Tapinarof) is a natural aryl hydrocarbon receptor (AhR) agonist with anti-inflammatory properties. |
| PC-45388 |
Ezutromid
Utrophin upregulator, AhR antagonist
|
Ezutromid (SMT C1100, VOX-C1100, BMN 195) is the first orally bioavailable small molecule utrophin upregulator with EC50 of 0.91 uM, directly binds aryl hydrocarbon receptor (AhR) with an apparent KD of 50 nM, behaves as an AhR antagonist. |
| PC-45600 |
AhR agonist ITE
AhR agonist
|
AhR agonist ITE is a endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro and in vivo. |
| PC-26733 |
PM-4321
AhR antagonist
|
PM-4321 is a potent, selective aryl hydrocarbon receptor (AhR) modulator profiled as part of an AhR antagonist, inhibits TCDD-induced AhR activation with IC50 of 2 nM. |
| PC-26676 |
CB7993113
AHR antagonist
|
CB7993113 is a potent, selective aryl hydrocarbon receptor (AhR) antagonist, blocks DMBA-induced AHR-dependent reporter activity with IC50 of 0.33 uM. |
| PC-26120 |
AFP464
HIF-1α inhibitor, AhR ligand
|
AFP464 (NSC710464) is a prodrug form of Aminoflavone and a small molecule aryl hydrocarbon receptor (AhR) ligand, inhibits HIF-1alpha expression in an AhR-independent fashion (IC50=0.25 uM). |
| PC-26119 |
Aminoflavone
AhR ligand
|
Aminoflavone is a small molecule aryl hydrocarbon receptor (AhR) ligand, inhibits HIF-1alpha expression in an AhR-independent fashion, also inhibits α6-integrin expression and breast cancer sphere-initiating capacity. |
| PC-26117 |
ZSTK3744 hydrochloride
AhR agonist
|
ZSTK3744 hydrochloride is a small molecule Aryl hydrocarbon receptor (AhR) agonist, exhibits cell growth inhibitory activity with IC50 of 0.87 nM for chemotherapy-resistant TNBC MDA-MB-468 cells. |
| PC-26116 |
ZSTK3744
AhR agonist
|
ZSTK3744 is a small molecule Aryl hydrocarbon receptor (AhR) agonist, exhibits cell growth inhibitory activity with IC50 of 0.87 nM for chemotherapy-resistant TNBC MDA-MB-468 cells. |
| PC-23914 |
Indirubin
AHR ligand
|
Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against CML, is a high affinity ligand of aryl hydrocarbon receptor (AHR) with dissociation constant (KD) value of 46.6 nM. |
