| Cat. No. |
Product Name |
Information |
| PC-42599 |
TAK-715
p38α inhibitor
|
TAK-715 is a potent, selective, orally active p38α MAPK inhibitor with IC50 of 7.1 nM. |
| PC-42566 |
SCIO-469
p38α MAPK inhibitor
|
Talmapimod (SCIO469) is a potent, selective p38α MAPK inhibitor with IC50 of 9 nM. |
| PC-42662 |
PD 169316
p38 MAPK inhibitor
|
PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM. |
| PC-42059 |
TA-02
p38 MAPK inhibitor
|
TA-02 is a potent p38 MAPK inhibitor with IC50 of 20 nM. |
| PC-42512 |
SB 202190
p38 MAPK inhibitor
|
SB 202190 (SB202190, SB-202190) is a potent inhibitor p38α and p38β with IC50 of 50 nM and 100 nM respectively. |
| PC-42526 |
VX-745
p38α MAPK inhibitor
|
Neflamapimod (VX-745) is a potent and selective p38α kinase inhibitor with IC50 of 9 nM. |
| PC-42520 |
Doramapimod
p38 MAPK inhibitor
|
Doramapimod (BIRB-796) is a highly potent p38 MAPK inhibitor with Kd of 0.1 nM. |
| PC-24763 |
GLPG0259
MAPKAPK5 inhibitor
|
GLPG0259 is a potent, specific, ATP-competitive and orally bioavailable mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5, PRAK, MK5) inhibitor. |
| PC-24303 |
MAPK13-IN-1
MAPK13 inhibitor
|
MPAK13-IN-1 (Compound 61) is a specific MAPK13 (p38δ) inhibitor with IC50 of 620 nM. |
| PC-23866 |
ULTR-p38i 2015
p38α inhibitor
|
ULTR-p38i 2015 is a potent, selective type 1.5 p38α inhibitor with IC50 of 4.8 nM, specifically inhibits p38α and p38β. |
| PC-23072 |
GEn-1124
p38α/MK2 modulator
|
GEn-1124 is a first-in-class small molecule modulator of p38α/MK2 signaling targeted to a pocket near the ED substrate binding domain of p38α, destabilizes the MK2: p38 complex. |
| PC-23071 |
UM101
p38α inhibitor
|
UM101 is a specific, noncatalytic, substrate-selective p38α MAPK inhibitor, targest the ED substrate-docking site and exerts anti-inflammatory effects. |
