PD 169316 | p38 MAPK inhibitor | Probechem Biochemicals

Chemical Structure : PD 169316

CAS No.: 152121-53-4

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PD 169316 (PD169316, PD-169316)

货号: PC-42662Not For Human Use, Lab Use Only.

PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.

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10 mg	￥880	In stock
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50 mg	￥2280	In stock
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PD 169316 is a potent, selective p38 MAPK inhibitor with IC50 of 89 nM.
PD 169316 displays >100-fold selectivity over ERK, PKA, PKCα.
PD 169316 prevent p38 phosphorylation while promotes the phosphorylation of the pro-survival SAPK/JNK and ERK;

物理化学性质&存储条件

分子量	360.3412
分子式	C20H13FN4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyridine, 4-[4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl]-

参考文献

1. Gallagher TF, et al. Bioorg Med Chem. 1997 Jan;5(1):49-64.

2. Krishnamoorthy M, et al. J Biochem. 2009 Feb;145(2):177-84.

3. Kozawa O, et al. Cell Signal. 2000 Jul;12(7):447-50.

PD 169316 (PD169316, PD-169316)

生物&药学活性

物理化学性质&存储条件

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PD 169316 (PD169316, PD-169316)

生物&药学活性

物理化学性质&存储条件

参考文献

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