TAM Receptor (Tyro3-Axl-Mer) (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofTAM Receptor (Tyro3-Axl-Mer) TAM Receptor (Tyro3-Axl-Mer)

Cat. No.	Product Name	Information
PC-23042	UNC8969 Mer/Axl inhibitor	UNC8969 is a potent, selective, macrocyclic dual MerTK/Axl inhibitor with IC50 of 1.1/5.3 nM respectively, >12-fold selectivity over TYRO3 and FLT3.
PC-23041	A-910 Mer/Axl inhibitor	A-910 is a highly potent and selective, orally active dual MerTK/Axl inhibitor with IC50 of 0.2/0.9 nM respectively, >200-fold selective over Tyro3.
PC-20332	INCB081776 AXL/MER inhibitor	INCB081776 is a potent and selective dual inhibitor of AXL and MERTK with IC50 of 16 and 14 nM respectively, 30-fold selectivity over TYRO3.
PC-50012	S49076 hydrochloride	S49076 hydrochloride is a potent, ATP-competitive tyrosine kinase inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 of <20 nM, also potently inhibits the kinase activity of mutated isoforms of MET (D1246N, Y1248D, Y1248H) and FGFR1/2.

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