| Cat. No. |
Product Name |
Information |
| PC-45970 |
BAY 61-3606
Syk inhibitor
|
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
| PC-44143 |
BAY 61-3606 dihydrochloride
Syk inhibitor
|
BAY 61-3606 dihydrochloride is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
| PC-43303 |
PRT-060318
SYK inhibitor
|
PRT-060318 is a potent and selective Syk inhibitor with IC50 of 4 nM. |
| PC-45082 |
RO9021
Syk inhibitor
|
RO9021 is an orally bioavailable, ATP-competitive, highly selective inhibitor of Syk kinase with IC50 of 5.6 nM. |
| PC-26566 |
GSK143 dihydrochloride
Syk inhibitor
|
GSK143 dihydrochloride is a highly potent, selective, orally efficacious Syk inhibitor with pIC50 of 7.5, >600-fold selective over ZAP-70. |
| PC-26203 |
MT-SYK-03
cSrc/SYK inhibitor
|
MT-SYK-03 is selective orally available inhibitor of cSrc and SYK kinases, inhibits cSrc and SYK with IC50 of 14.2 and 23 nM respectively. |
| PC-23775 |
UNC10225387B
Multikinase inhibitor
|
UNC10225387B is a multi-kinase inhibitor, cocktail of UNC10225387B, UNC10225263A and UNC10225761A, promotes stem-cell-like chimeric antigen receptor T cells (CAR T cells). |
| PC-23774 |
UNC10225263A
Multikinase inhibitor
|
UNC10225263A is a multi-kinase inhibitor, cocktail of UNC10225387B, UNC10225263A and UNC10225761A, promotes stem-cell-like chimeric antigen receptor T cells (CAR T cells). |
| PC-23773 |
UNC10225761A
Multikinase inhibitor
|
UNC10225761A is a multi-kinase inhibitor, cocktail of UNC10225387B, UNC10225263A and UNC10225761A, promotes stem-cell-like chimeric antigen receptor T cells (CAR T cells). |
| PC-21066 |
ZAP-70 inhibitor 20
ZAP-70 inhibitor
|
ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk. |
| PC-21065 |
ZAP-70 inhibitor 26
ZAP-70 inhibitor
|
ZAP-70 inhibitor 26 is a potent, highly selective ZAP-70 kinase inhibitor with IC50 of 88 nM, shows high selectivity over structurally related Syk (IC50>10 uM). |
| PC-20602 |
BI 1342561
Syk inhibitor
|
BI 1342561 is a novel potent and selective SYK inhibitor developed to treat severe asthma. |