| Cat. No. |
Product Name |
Information |
| PC-42318 |
ETH2120
Sodium ionophore
|
ETH2120 is a sodium ionophore, relieves hydrogen-dependent caffeate reduction and completely abolishes ATP synthesis in cells. |
| PC-42201 |
Nicainoprol
Sodium channels inhibitor
|
A sodium channels blocker, adrenergic receptor antagonist and class 1 antiarrhythmic agent.. |
| PC-45079 |
ICA-121431
Nav1.3/Nav1.1 inhibitor
|
ICA-121431 is a potent, selective small molecule human Nav1.3/Nav1.1 channel inhibitor with IC50 of 19 nM. |
| PC-45762 |
XEN-907
NaV1.7 inhibitor
|
XEN-907 (XEN907) is a potent, selective NaV1.7 blocker with IC50 of 3 nM. |
| PC-42804 |
A-803467
Nav1.8 inhibitor
|
A-803467 (A803467) potent and selective Nav1.8 sodium channel blocker with IC50 of 8 nM. |
| PC-45068 |
Eleclazine hydrochloride
I(Na,late) inhibitor
|
Eleclazine (GS6615) hydrochloride is a potent, and selective inhibitor of Late sodium current (late INa) for treatment of long QT-3 syndrome (LQT-3), hypertrophic cardiomyopathy (HCM), and ventricular tachycardia–ventricular fibrillation (VT–VF). |
| PC-45252 |
Flecainide acetate
Nav1.5 inhibitor, RyR2 inhibitor
|
A class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias, works by blocking the Nav1.5 sodium channel in the heart, slowing the upstroke of the cardiac action potential. |
| PC-26525 |
S3226
NHE3 inhibitor
|
S3226 is a potent, selective Na+/H+ exchanger subtype 3 (NHE3, SLC9A3) inhibitor with IC50 of 0.02 uM (hNHE3), shows >100-fold selectivity over hNHE1 and rbNHE2. |
| PC-26470 |
AM-2099
NaV1.7 inhibitor
|
AM-2099 is a potent, selective inhibitor of voltage-gated sodium channel NaV1.7 with IC50 of 0.16 uM (hNaV1.7), with no actiivity against hNaV1.5. |
| PC-26048 |
Eleclazine
I(Na,late) inhibitor
|
Eleclazine (GS6615) hydrochloride is a potent, and selective inhibitor of Late sodium current (late INa) for treatment of long QT-3 syndrome (LQT-3), hypertrophic cardiomyopathy (HCM), and ventricular tachycardia–ventricular fibrillation (VT–VF). |
| PC-25144 |
GSK3β-Nav1.6 inhibitor 1063
GSK3β/Nav1.6 inhibitor
|
GSK3β-Nav1.6 inhibitor 1063 is a brain-penetrant small molecule that selectively disrupts GSK3β/Nav1.6 complex formation (IC50=26.2 uM) and inhibits Nav1.6 currents in an isoform-specific manner. |
| PC-25089 |
Repunapanor
NHE3 inhibitor
|
Repunapanor is a potent, selective Na+/H+ exchanger 3 (NHE3) inhibitor. |
