| Cat. No. |
Product Name |
Information |
| PC-25814 |
DY-III-281
SARS-CoV entry inhibitor
|
DY-III-281 is a SARS-CoV-2 small-molecule entry inhibitor with IC50 of 0.62 uM and 0.44 uM for SARS-CoV-1-S and SARS-CoV-2-S pseudoviruses. |
| PC-25730 |
H135
SARS-CoV-2 Mpro inhibitor
|
H35 is a potent and selective inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 12.7 nM, exerts broad anti-SARS-CoV-2 activity. |
| PC-25647 |
SARS-CoV-2 NSP14 inhibitor C10
SARS-CoV-2 NSP14 inhibitor
|
SARS-CoV-2 NSP14 inhibitor C10 is a potent, selective non-nucleoside inhibitor of SARS-CoV-2 nonstructural protein 14 (NSP14) with IC50 of 0.34 uM, exhibits potent antiviral activity and reverses NSP14-driven host modulation. |
| PC-25609 |
Licoflavone C
SARS-CoV-2 nsp13 inhibitor
|
Licoflavone C is a prenyl-flavone extracted from Genista ephedroides and SARS-CoV-2 nsp13 inhibitor, block both SARS-CoV-2 nps13 unwinding and ATPase activities with IC50 of 1.34 uM and 24.6 uM respectively. |
| PC-25564 |
SARS-CoV-2 Mpro inhibitor H102
SARS-CoV-2 Mpro inhibitor
|
SARS-CoV-2 Mpro inhibitor H102 is a potent covalent inhibitor of SARS-CoV-2 Mpro with IC50 of 8.8 nM. |
| PC-25310 |
SARS-CoV-2 Mpro inhibitor 18
Mpro inhibitor
|
SARS-CoV-2 Mpro inhibitor 18 is potent, reversible covalent inhibitor of SARS-CoV-2 Mpro with IC50 of 8 nM, inhibits virus induced cytopathic effect (CPE) with EC50 of 58 nM. |
| PC-25261 |
DNDI-6510
SARS-CoV-2 Mpro inhibitor
|
DNDI-6510 ((S)-x38) is a non-covalent, potent SARS-CoV-2, isoquinoline-based MPro inhibitor with IC50 of 40 nM, SARS-CoV-2 EC50 of 0.17 uM (A549 cells). |
| PC-24841 |
Dihydrotanshinone I
MERS-CoV inhibitor, MAN1B1 inhibitor
|
Dihydrotanshinone I (DHT I) is a natural compound extracted from Salvia miltiorrhiza Bunge, exhibits entry-blocking effect for MERS-CoV, also potentially inhibits mannosidase alpha class 1B member 1 (MAN1B1). |
| PC-24641 |
ISM3312
Mpro inhibitor
|
ISM3312 is a potent, irreversible covalent broad-spectrum inhibitor of human coronavirus main protease (Mpro) with IC50 of 14 nM, exhibits potent cellular potency in VeroE6 cell lines with EC50 of 71 nM. |
| PC-24603 |
Bafilomycin D
V-ATPase inhibitor, SARS-CoV-2 inhibitor
|
Bafilomycin D (BafD) is a specific V-ATPase inhibitor and potent nanomolar inhibitor of SARS-CoV-2 Omicron subvariants BA.5 and BA.2. |
| PC-24591 |
Ac-Glu-Orn-Arg-kbt
TMPRSS11D inhibitor
|
PM-5 (Ac-Glu-Orn-Arg-kbt) is a potent, selective TMPRSS2 inhibitor with IC50 of 6.2 nM, exhibits selectivity for TMPRSS2 over TMPRSS11D. |
| PC-24590 |
Ac-Glu-Glu-Arg-kbt
TMPRSS11D inhibitor
|
PM-3 (Ac-Glu-Glu-Arg-kbt) is a potent dual TMPRSS11D and TMPRSS2 inhibitor with IC50 of 7.1 nM and 3.2 nM respectively. |
