| Cat. No. |
Product Name |
Information |
| PC-38282 |
P2165
Spike RBD-ACE2 inhibitor
|
P2165 (P-2165) is a anticoronaviruse chemical probe that inhibit SARS-CoV-2 Spike binding to human ACE2 receptor. |
| PC-38281 |
P2119
Spike RBD-ACE2 inhibitor
|
P2119 (P-2119) is an anticoronaviruse chemical probe that inhibit SARS-CoV-2 Spike binding to human ACE2 receptor. |
| PC-38259 |
MM3122
TMPRSS2 inhibitor
|
MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
| PC-38238 |
DX600
ACE2 inhibitor
|
DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
Spike RBD-ACE2 inhibitor
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
Ensitrelvir
3CLpro inhibitor
|
Ensitrelvir (S-217622, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-35231 |
GC376
3CLpro inhibitor
|
GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays. |
| PC-25870 |
IMB-9C
HR1/HR2 inhibitor
|
IMB-9C is a specific small molecule inhibitor of heptad repeat 1/heptad repeat 2 (HR1/HR2) interaction, inhibits SARS-CoV-2-S-mediated cell-cell fusion. |
| PC-25844 |
CNiBuC
SARS-CoV-2 RdRp inhibitor
|
CNiBuC is the 5′-isobutyril ester prodrug of 1'-cyanocytidine and a reversible, competitive inhibitor of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp), shows anti-SARS-CoV-2 activity with EC50 of 3.6 uM in Vero cells. |
| PC-25823 |
Avoralstat
Plasma kallikrein inhibitor, TMPRSS2 inhibitor
|
Avoralstat (BCX4161) is a potent and orally active plasma kallikrein inhibitor, also is a potent, selective Transmembrane protease, serine 2 (TMPRSS2) inhibitor (IC50=2.73 nM). |
