| Cat. No. |
Product Name |
Information |
| PC-35761 |
RSV inhibitor compound 1
RSV fusion inhibitor
|
RSV inhibitor compound 1 is a novel potent, orally bioavailable RSV fusion inhibitor with EC50 of 2 nM (RSV Long strain infected HEp-2 cells) without significant cytotoxicity (CC50>100 uM). |
| PC-63344 |
Enzaplatovir
RSV fusion inhibitor
|
Enzaplatovir (BTA-585, BTA-C585) is an orally bioavailable RSV fusion protein inhibitor for the treatment of respiratory syncytial virus infections.. |
| PC-63296 |
Sisunatovir
RSV inhibitor
|
Sisunatovir (RV521) is a potent, orally active, small-molecule inhibitor of RSV fusion with IC50 of 1.4 nM and 1.0 nM for clinical isolates of RSV-A and RSV-B viruses. |
| PC-63269 |
BMS433771
RSV fusion inhibitor
|
BMS433771 (BMS-433771) is a potent, orally active RSV fusion inhibitor, exhibits excellent potency against multiple laboratory and clinical isolates of both group A and B viruses with mean EC50 of 20 nM. |
| PC-63268 |
VP-14637
RSV fusion inhibitor
|
VP-14637 (MDT-637) is a novel RSV fusion inhibitor with EC50 of 1.4 nM, reduces RSV replication by inhibition of the F-protein function. |
| PC-43310 |
RSV604 racemate
RSV inhibitor
|
RSV604 racemate is a racemic mixture, shows less potency against strains of respiratory syncytial virus (RSV) than the S-isomer (RSV604).. |
| PC-43309 |
RSV604
RSV inhibitor
|
RSV604 (RSV-604) is a potent respiratory syncytial virus (RSV) inhibitor with EC50 of 0.86 uM in XTT assay, targets the nucleocapsid protein and is active post-RSV infection. |
| PC-43307 |
ALS-8176
RSV polymerase inhibitor
|
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM. |
| PC-43306 |
ALS-8112
RSV polymerase inhibitor
|
ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase (IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
| PC-42807 |
TMC353121
RSV inhibitor
|
TMC353121 is a potent respiratory syncytial virus (RSV) fusion inhibitor with pEC50 of 9.9, shows activity against groups A and B RSV and against a panel of clinical isolates with equal potency (EC50<0.1 ng/mL). |
| PC-63102 |
GS1
RSV fusion inhibitor
|
GS1 (GS-1) is a close structural analog of GS-5806 that acts an RSV fusion inhibitor, blocks virus entry by inhibiting the fusion of the viral envelope with the host cell membrane, shows antiviral efficacy in the bovine RSV models. |
| PC-61493 |
JNJ-53718678
RSV fusion inhibitor
|
Rilematovir (JNJ-53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV. |
