| Cat. No. |
Product Name |
Information |
| PC-35737 |
SB-772077B
ROCK inhibitor
|
SB-772077B (SB772077B, SB77) is a potent, selective Rho kinase (ROCK) inhibitor with IC50 of 5.6 nM and 6.0 nM for ROCK1 and ROCK2, respectively. |
| PC-35150 |
DJ4
ROCK/MRCK inhibitor
|
DJ4 (ROCK inhibitor DJ4) is a potent, selective, ATP-competitive inhibitor of ROCK1/2 and MRCKα/β with IC50 of 5/50 nM and 10/100 nM, respectively. |
| PC-43479 |
SR-3677
ROCK2 inhibitor
|
SR-3677 is a potent and selective ROCK-II inhibitor with biochemical IC50 of 3 nM, inhibits myosin light chain bisphosphorylation (ppMLC) with IC50 of 3.5 nM in cell-based assays. |
| PC-63524 |
BDP5290
MRCK inhibitor
|
BDP5290 (BDP00005290) is a potent myotonic dystrophy kinase-related CDC42-binding kinase (MRCK) inhibitor with Ki of 10/4 nM for MRCKα/β, respectively. |
| PC-63523 |
BDP9066
MRCK inhibitor
|
BDP9066 (BDP-9066) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM, >100-fold selectivity over related ROCK1 or ROCK2. |
| PC-63522 |
BDP8900
MRCK inhibitor
|
BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2. |
| PC-43437 |
Thiazovivin
ROCK inhibitor
|
Thiazovivin is a small molecule inhibitor of ROCK, dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts. |
| PC-62716 |
Netarsudil dihydrochloride
ROCK inhibitor
|
Netarsudil (AR-13324) dihydrochlorideis a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
| PC-62715 |
Verosudil
ROCK inhibitor
|
Verosudil (AR-12286) is a potent ROCK inhibitor with Ki of 2 nM for both ROCK1 and ROCK2. |
| PC-62714 |
Netarsudil
ROCK inhibitor
|
Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2. |
| PC-61252 |
FPND
ROCK1 inhibitor
|
FPND (FPMINT) is a novel specific ROCK1 kinase inhibitor with IC50 of 11.2 uM, without inhibitory activity against ROCK2, also is an inhibitor of equilibrative nucleoside transporter ENT1 and ENT2. |
| PC-60681 |
PF-4950834
ROCK inhibitor
|
PF-4950834 is a potent, selective, ATP-competitive and orally acitve Rho kinase (ROCK) inhibitor with IC50 of 33.1 and 8.5 nM for ROCK1 and ROCK2, respectively. |
