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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Proteasome

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Cat. No. Product Name Information
PC-21187

KDT-11

Rpn-13 inhibitor

KDT-11 is a specific, reversible peptidomimetic binder inhibitor of Rpn-13 with binding KD of 3 uM, selectively inhibit proliferation of a broad range of cancer cell lines (NCI60, IC50=5 uM), but not non-malignant cells.
PC-20757

BT317

LonP1 inhibitor

BT317 is a small molecule dual inhibitor of mitochondrial Lon Peptidase 1 (LonP1) and CT-L proteasome, subsequently induces ROS accumulation and autophagy-dependent cell death in high-grade IDH1 mutated astrocytoma lines.

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