| Cat. No. |
Product Name |
Information |
| PC-35139 |
BAY-386
PAR1 antagonist
|
BAY-386 (BAY386) is a potent, specific and reversible PAR-1 antagonist with IC50 of 10 nM (HEK cell) and binding IC50 of 56 nM, without affinity for PAR-4 (IC50>10 uM). |
| PC-62640 |
Parmodulin 2
PAR-1 antagonist
|
Parmodulin 2 (ML161) is a potent, specific antagonist of PAR-1, specifically inhibits thrombin-tethered ligand (TL) peptide-mediated platelet aggregation with IC50 of 7 uM. |
| PC-62125 |
ML354
PAR4 antagonist
|
ML354 (VU0099704) is a novel potent and selective PAR4 antagonist with IC50 of 140 nM, displays 71-fold selectivity versus PAR-1. |
| PC-62088 |
I-191
PAR2 antagonist
|
I-191 (I191, I 191) is a novel potent, selective protease-activated receptor 2 (PAR2) antagonist with pIC50 of 7.2 in cell-based assays. |
| PC-62040 |
JF-5
PAR1 antagonist
|
JF5 (PAR1 inhibitor JF5) is an allosteric inhibitor of PAR1 that binds to helix 8 of the receptor. |
| PC-61618 |
GB83
PAR2 antagonist
|
GB83 is a selective, reversible PAR2 (Protease-activated receptor 2) antagonist with IC50 of 2 uM. |
| PC-61561 |
ENMD-1068
PAR2 inhibitor
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
| PC-61560 |
ENMD-1068 hydrochloride
PAR2 antagonist
|
ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling. |
| PC-61308 |
Atopaxar hydrobromide
PAR1 antagonist
|
Atopaxar hydrobromide (E5555) is a potent, reversible protease-activated receptor-1 (PAR-1) antagonist with IC50 of 19 nM. |
| PC-61307 |
Atopaxar
PAR1 antagonist
|
Atopaxar (E5555) is a potent, reversible protease-activated receptor-1 (PAR-1) antagonist with IC50 of 19 nM. |
| PC-61306 |
SCH 79797
PAR1 antagonist
|
SCH79797 is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
| PC-61305 |
SCH 79797 dihydrochloride
PAR1 antagonist
|
SCH79797 dihydrochloride is a potent, selective competitive and nonpeptide PAR-1 antagonist with IC50 of 70 nM. |
